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Vitamin C: Vitamin C protects the sperm against the destructive effects of free radicals, which also contribute to the development of many disorders. Vitamin C supplementation increases sperm count. In one study, two months after 30 infertile but otherwise healthy men began receiving 1 g of the vitamin daily, all of their wives had become pregnant.

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Author affiliations: mcconnell brain imaging center, montreal neurological institute, montreal, quebec drs boileau, dagher, leyton, gunn, diksic, and benkelfat departments of neurology and neurosurgery drs boileau, dagher, gunn, and diksic ; and psychiatry drs leyton and benkelfat ; , mcgill university, montreal; and department of psychiatry, mackenzie centre, university of alberta, edmonton dr baker. Impaired the healing of a cutaneous ulcer in a patient with diabetes. Accepted for Publication: November 24, 2004. Correspondence: Patrick R. Carrington, MD, Department of Dermatology, University of Arkansas for Medical Sciences, 4301 W Markham, Slot 576, Little Rock, AR 72205 Patrick rrington med.va.gov ; . Financial Disclosure: None and lunesta.

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Vallance, Bruce A., Kenneth Croitoru, and Stephen M. Collins. T lymphocyte-dependent and -independent intestinal smooth muscle dysfunction in the T. spiralis-infected mouse. Am. J. Physiol. 275 Gastrointest. Liver Physiol. 38 ; : G1157G1165, 1998.--We examined the profile of increased intestinal muscle contractility after primary infection with Trichinella spiralis in the mouse, correlating it with parasite expulsion. We also examined the extent to which the changes in muscle contraction were T lymphocyte dependent, by infecting athymic and SCID mice. Infection was accompanied by increased tension development by intestinal muscle. Two components of this response were identified, a rapid peak increase in tension generation observed on day 6 postinfection, and a smaller but sustained increase in tension evident thereafter in euthymic BALB c mice. The peak muscle response was significantly delayed in infected athymic and SCID mice, along with a corresponding reduction in the magnitude of the sustained component. These changes were accompanied by reduced parasite expulsion in athymic and SCID mice, compared with euthymic mice. Reconstitution of T cell function in athymic mice restored both the acute and sustained profile of muscle contraction seen in euthymic mice, and this was accompanied by faster expulsion of the worms. These results identify T cell-dependent and -independent components of the muscle response to nematode infection in the mouse and suggest that the onset of the peak contractile response, as well as the magnitude of the sustained muscle response, contributes to parasite eviction from the gut. inflammation; gastrointestinal motility and lysine.

A 61-year-old man was admitted to the hospital with symptoms occurring two and one-half months prior to admission. While driving his car, he noted the sudden onset of vertigo and a slight change in hearing. This feeling passed in a few seconds. During the next two weeks he had a constant feeling of unsteadiness while walking but no longer had vertigo. There was no incoordination of the extremities, nausea, or vomiting. The unsteadiness gradually improved, but one morning upon awakening he had another vertiginous episode. Shortly thereafter he noted his speech was slurred. He was taken to a local hospital within five hours and both the vertigo and speech difficulty disappeared. There was no associated weakness of the extremities. Ten years ago while hospitalized for a myocardial infarction, he had a stroke. The only residual effect was a decreased sensation on the left and mechlorethamine.

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